Cancer/Leishmania treatment with LupArte2.0 ® capsules/tablets (Active ingredient-optimized mixture of Artemisia annua plant leaves and 30: 1 Artemisia annua extract, Lupovet Ltd) in cats/dogs (in line with the artemisinin-based combination therapy (ACT) of the WHO):
1. Preparation phase
Cancer: Anti-inflammatory treatment (with Meloxicam as anti-inflammatory suspension); surgical removal of the tumor (no matter if metastasis has occurred or not), if possible; initial serum iron measurement
Leishmaniosis: initial serum iron measurement
with LupArte 2.0 ®
- Determination of the serum iron (normal range between 140 – 170 µg/dl), often too low in case of a malignant tumor
- At the same time iron must be given either:
A) orally in form of Ferrosanol® capsules (100 mg/capsule) or Ferrosanol® drops (30 mg/ml); dosage: 100 mg/30 kg weight twice daily initially and/or
B) per injection of Ursoferran® (100mg/ml); dosage: 100 mg/10 kg weight initially two times a week (this is cheaper and more effective)
The iron application must be continued for the entire treatment period and adjusted accordingly to reach the (high) level of 250 + 30 µg/dl.
- From the fourth day onward, the animal must be treated with LupArte 2.0® capsules/tablets three times daily. The dosage is about 1400 mg/m² body surface and per day (see conversion table below). It is given in three partial dosages approximately every 8 hours if possible. The capsules shall be given 1 – 2 hours before feeding and – if possible – without meat in a little piece of Gouda cheese. Giving four dosages a day may be more helpful than giving three dosages a day since we know that this drug has a relatively short half-life period.
During treatment the serum iron must be continuously controlled and adjusted if necessary.
|weight [kg]||surface of the body [m²]|
Regular iron serum check:
Target: 250 + 30 µg/dl.; adjusted iron substitution (oral/parenteral); life-long treatment with LupArte2.0® with the standard dosage